منابع مشابه
Diabetic neuropathy: Past, present, and future
Background: A sedentary lifestyle and an unhealthy diet have considerably increased the incidence of diabetes mellitus worldwide in recent decades, which has generated a high rate of associated chronic complications. Methods: A narrative review was performed in MEDLINE, EMBASES and SciELO databases, including 162 articles. Results: Diabetic neuropathy (DN) is the most common of these complic...
متن کاملAGEs and diabetic retinopathy.
The pathogenesis of diabetic retinopathy is multifactorial, and a range of hyperglycemia-linked pathways have been implicated in the initiation and progression of this condition. All cells in the retina are affected by the diabetic milieu, and in view of such disease and tissue complexity, it is unlikely that any single process is solely responsible for retinal pathophysiology. Nevertheless, es...
متن کاملEMLA-Induced Skin Wrinkling for the Detection of Diabetic Neuropathy
OBJECTIVE To determine the usefulness of Eutectic Mixture of Local Anesthetic (EMLA)-induced stimulated skin wrinkling (SSW) to detect diabetic sensorimotor polyneuropathy (DSPN). RESEARCH DESIGN AND METHODS Two hundred and ten diabetics were prospectively recruited (mean age 58.5 ± 12.7 years) from a large tertiary center from 2009 to 2011. EMLA was applied to the tips of digits 2, 3, and 4 ...
متن کاملNeuropathological alterations in diabetic truncal neuropathy: evaluation by skin biopsy.
OBJECTIVES To describe the neuropathological features in skin biopsies from patients with diabetic truncal neuropathy. METHODS Three patients with diabetic truncal neuropathy underwent skin biopsies from both symptomatic and asymptomatic regions of the chest and trunk. After local anaesthesia, biopsies were performed using a 3 mm diameter punch device (Acupunch). Intraepidermal nerve fibres (...
متن کاملSkin microcirculation of the foot in diabetic neuropathy.
1. In the feet of patients with diabetic neuropathy, total skin blood flow is increased due to an increased shunt flow. The question is, does this increased anastomotic shunt flow lead to either under- or overperfused nutritive capillaries. 2. To solve this question, skin microcirculation tests of the left big toe were performed in 20 healthy control subjects and in 40 insulin-dependent diabeti...
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ژورنال
عنوان ژورنال: BMC Endocrine Disorders
سال: 2021
ISSN: 1472-6823
DOI: 10.1186/s12902-021-00697-7